A Review Of akorn codeine

The respiratory depression entails a discount from the responsiveness in the Mind stem respiratory centers to each increases in carbon dioxide stress also to electrical stimulation.

Promethazine is metabolized with the liver to a range of inactive metabolites for instance sulfoxides of promethazine, N-demethylpromethazine and other glucuronides.

Hazard Summary Promethazine HCl and codeine phosphate oral Remedy isn't recommended for use in pregnant Girls, such as for the duration of or immediately prior to labor.

are pregnant. Usage of Promethazine Hydrochloride and Codeine Phosphate Oral Solution during pregnancy may cause withdrawal signs with your newborn baby that could be daily life-threatening if not identified and addressed. Inform your healthcare supplier immediately if you are Expecting or Feel you might be Expecting. •

are breastfeeding or decide to breastfeed. Codeine Phosphate passes into your breast milk and may harm your child. Both you and your Health care provider really should examine whether you must choose Promethazine with Codeine Oral Answer or breastfeed. You shouldn't do both.

Promethazine HCl and codeine phosphate oral Option, like other opioids, may be diverted for non-clinical use into illicit channels of distribution.

Lower blood pressure. A sudden fall in blood pressure level can transpire in a lot of people through procedure with Promethazine Hydrochloride and Codeine Phosphate Oral Remedy which may perhaps result in you to really feel dizzy, faint, lightheaded, or weak, especially when you arise (orthostatic hypotension). Your chance of having this issue can be enhanced if you're taking Promethazine Hydrochloride and Codeine Phosphate Oral Alternative with particular other medicines that lower blood pressure.

five.15 Enhanced Threat of Seizures in Sufferers with Seizure Disorders The codeine and promethazine in promethazine HCl and codeine phosphate oral solution may possibly improve the frequency of seizures in individuals with seizure Problems, and could boost the possibility of seizures taking place in other clinical settings linked to seizures.

Cure of Overdose Treatment of overdosage is pushed by the general scientific presentation, and consists of discontinuation of promethazine HCl and codeine phosphate oral Resolution along with institution of suitable therapy. Give Most important attention to the reestablishment of satisfactory respiratory exchange by way of provision of the patent and guarded airway plus the establishment of assisted or managed ventilation.

Scientific Issues Infants subjected to promethazine HCl and codeine phosphate oral Answer through breast milk really should be monitored for excessive sedation and respiratory despair.

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Your healthcare supplier may possibly do blood assessments to check for adrenal gland difficulties. Contact your healthcare service provider immediately In case you have any of those signs:

Neuroleptic malignant syndrome (NMS) which can lead to Dying. Notify your healthcare provider straight away if you have any of the next signs and symptoms of NMS:

Impaired secretion from sweat legal lean for sale glands subsequent harmful doses of medications with anticholinergic Uncomfortable side effects may well predispose to hyperthermia.